Table 2.
The scores for RCFT copying, the LB and Cherrier's six categories classification of groups of healthy, very mild AD, and mild/moderate AD subjects.
| Domais | Full score | Healthy | Very mild AD | Mil/moderate AD |
F values |
p values |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | (CDR0) | n | (CDR 0.5) | n | (CDR 1&2) | |||||||
| RCFT | ||||||||||||
| Copying total score | 36.0 | 40 | 30.3 (4.9) | 40 | 26.1 (8.6)a | 31 | 21.5 (9.7)ab | 11.0 | 0.00** | |||
| Cherrier's six categories | ||||||||||||
| Gestalt (unit 2,3,4,5,13,16) | 2.0 | 1.9 (0.2) | 1.7 (0.5) | 1.4 (0.6)ab | 10.79 | 0.00** | ||||||
| Detail (unit 6,7,8,10,11,12,15) | 2.0 | 1.6 (0.4) | 1.3 (0.5)a | 1.0 (0.6)a | 10.72 | 0.00** | ||||||
| Right (unit 14) | 2.0 | 1.7 (0.6) | 1.5 (0.7) | 1.2 (0.9)a | 5.09 | 0.01* | ||||||
| Left (unit 1) | 2.0 | 1.6 (0.6) | 1.2 (0.8)a | 0.8 (0.8)a | 10.16 | 0.00* | ||||||
| Upper (unit 9) | 2.0 | 1.8 (0.5) | 1.6 (0.8) | 1.4 (0.8) | 2.74 | 0.07 | ||||||
| Lower (unit 17,18) | 2.0 | 1.6 (0.5) | 1.4 (0.7) | 1.2 (0.7)a | 4.35 | 0.02* | ||||||
| LB (120 mm) | 60.0 | 40 | 0 (2.3) | 40 | -0.2 (3.4) | 31 | -0.4 (3.5) | 0.15 | 0.86 | |||
| LB (200 mm) | 100.0 | 40 | -0.2 (4.2) | 40 | -0.5 (4.3) | 31 | -1 (4.6) | 0.29 | 0.75 | |||
Means shown (SD), F values and p values (covariance effects). Significant differences among the three groups were shown on ANOVAs (*p<0.05, **p<0.001). On Tukey-Kramer post hoc tests, "a" was significantly lower than healthy, "b" was significantly lower than very mild AD. Using Cherrier's six categories classification (Neuropsychiatry Neuropsychol Behav Neurol, 1999;12:95-101). On the LB, the mean of deviations from the middle for 120 mm or 200 mm lines were calculated. CDR: Clinical Dementia Rating; RCFT: Rey-Osterrieth Complex Figure test; LB: Line Bisection test; AD: Alzheimer's disease.