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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Neuroimage. 2016 Oct 24;146:1003–1015. doi: 10.1016/j.neuroimage.2016.10.036

Fig. 5. NAc dopamine signals saturate only at very high frequency.

Fig. 5

(a) Dopamine oxidation detected by fixed potential (0.8 V) amperometry during MFB stimulation in a representative animal under conditions similar to the fMRI experiments. Each trace shows responses to a series of eight pulse trains delivered with the stimulation frequency indicated. (b) Normalized average amperometric responses (n = 3) measured over a range of frequencies including those used for behavioral and MRI experiments. Saturation is observed only at frequencies of 315 ± 32 Hz (mean ± s.d.).