. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: Otolaryngol Head Neck Surg. 2016 Oct 13;156(2):228–237. doi: 10.1177/0194599816671885

Table II.

Selected Randomized Controlled Trials for Integrative Medicine for Head and Neck Cancer Treatment

Study	Intervention	Outcome measured	Findings
Pisters (2001)⁶⁵	Green tea extract	Maximum-tolerated dose of green tea extract (Phase I Trial)	Maximum-tolerated dose was 4.2 g/m² once daily or 1.0 g/m² three times a day.
Steuer-Vogt (2001)³⁶	Mistletoe extract	Efficacy of mistletoe preparation as adjuvant therapy after surgery/radiation	Mistletoe had no effect on survival rates, cellular immune response, or quality of life
Worden (2015)³⁷	(−)-gossypol (AT-101)	Efficacy of AT-101 and chemotherapy for organ preservation in advanced laryngeal cancer	Ongoing clinical trial