Table 4. Factors associated with colorectal cancer mortality (N = 18,816).
| Factors | No. of deaths | 1,000 person- years | Crude HR | P-value |
|---|---|---|---|---|
| Age category | ||||
| < 50 | 0 | 0 | 1 | |
| 50–59 | 0 | 0 | NA | NA |
| 60–69 | 0 | 0 | NA | NA |
| 70–79 | 2 | 0.123 | NA | NA |
| ≥ 80 | 2 | 0.580 | NA | NA |
| Sex | ||||
| Female | 2 | 0.105 | 1 | |
| Male | 2 | 0.042 | 0.41 (0.06–2.92) | 0.374 |
| Current smoker | 0 | 0 | NA | NA |
| Family history of CRC | 0 | 0 | NA | NA |
| Comorbidities | ||||
| Ischemic heart diseases | 2 | 0.135 | 3.65 (0.51–25.9) | 0.196 |
| Chronic heart failure | 2 | 0.208 | 6.13 (0.86–43.6) | 0.070 |
| Peripheral vascular diseases | 2 | 0.290 | 9.59 (1.35–68.1) | 0.024 |
| Cerebral vascular diseases | 1 | 0.147 | 2.99 (0.31–28.7) | 0.344 |
| Dementia | 0 | 0 | NA | NA |
| COPD | 1 | 0.502 | 11.1 (1.15–106.5) | 0.037 |
| Collagen diseases | 0 | 0 | NA | NA |
| Peptic ulcer diseases | 3 | 0.094 | 3.39 (0.35–32.6) | 0.291 |
| Diabetes mellitus | 3 | 0.109 | 4.66 (0.48–44.8) | 0.183 |
| Chronic kidney diseases | 0 | 0 | NA | NA |
| Paresthesia | 0 | 0 | NA | NA |
| Leukemia | 0 | 0 | NA | NA |
| Malignant lymphoma | 0 | 0 | NA | NA |
| Liver cirrhosis | 0 | 0 | NA | NA |
| AIDS | 0 | 0 | NA | NA |
| Indication for colonoscopy | ||||
| Positive FIT | 1 | 0.060 | 1.00 (0.10–9.60) | 0.999 |
| Initial colonoscopy findings | ||||
| Polyp detection | 2 | 0.064 | 1.14 (0.16–8.07) | 0.898 |
| 10-mm adenoma detection† | 0 | 0 | NA | NA |
| 20-mm adenoma detection† | 0 | 0 | NA | NA |
| Therapeutic colonoscopies | 0 | 0 | NA | NA |
| Number of colonoscopies | ||||
| 1 | 0 | 0 | NA | NA |
| 2 | 3 | 0.130 | 1 | |
| 3 | 1 | 0.106 | 1.60 (0.17–15.3) | 0.686 |
| 4 | 0 | 0 | NA | NA |
| 5 | 0 | 0 | NA | NA |
| 6 | 0 | 0 | NA | NA |
| 7 | 0 | 0 | NA | NA |
†The crude and adjusted hazard ratios of 10-mm and 20-mm adenoma detection were calculated using imputation data.
CRC, colorectal cancer; COPD, chronic pulmonary disease; AIDS, acquired immune deficiency syndrome; FIT, fecal immunochemical test; HR, hazard ratio; NA, not applicable.