Table 1. Clinical and histopathological characteristics of the total MATCH cohort.
n | % |
SYK(T) median (IQR) |
P value |
SYK(S) median (IQR) |
P value |
SYK(L) median (IQR) |
P value | Performed test | ||
---|---|---|---|---|---|---|---|---|---|---|
Gender | Female | 112 | 46.7% | -4.24 (-4.60 • -3.72) | 0.11 | -4.81 (-5.47 • -4.14) | 0.18 | -4.76 (-5.16 • -4.17) | 0.40 | Mann-Whitney U |
Male | 128 | 53.3% | -4.05 (-4.58 • -3.50) | -4.63 (-5.27 • -3.93) | -4.66 (-5.19 • -4.03) | |||||
Age | 240 | 100% | -0.08 | 0.21 | -0.009 | 0.89 | -0.011 | 0.86 | Spearman's Rho | |
Tumor stage | Stage I | 60 | 25.0% | -4.31 (-4.71 • -3.67) | 0.31 | -4.62 (-5.21 • -3.96) | 0.037 | -4.73 (-5.26 • -4.28) | 0.45 | Jonckheere-Terpstra |
Stage II | 100 | 41.7% | -3.96 (-4.55 • -3.47) | -4.61 (-5.36 • -4.07) | -4.54 (-5.04 • -3.95) | |||||
Stage III | 80 | 33.3% | -4.15 (-4.58 • -3.68) | -4.98 (-5.70 • -4.19) | -4.81 (-5.30 • -4.33) | |||||
T status | T2 | 71 | 29.6% | -4.32 (-4.69 • -3.76) | 0.03 | -4.69 (-5.26 • -3.97) | 0.37 | -4.77 (-5.33 • -4.46) | 0.021 | Mann-Whitney U |
T3 | 169 | 70.4% | -4.05 (-4.57 • -3.56) | -4.70 (-5.43 • -4.08) | -4.65 (-5.11 • -4.04) | |||||
Nodal status | N0 ≥ 10 nodes assessed | 131 | 54.6% | -4.08 (-4.60 • -3.62) | 0.97 | -4.63 (-5.32 • -4.08) | 0.07 | -4.62 (-5.13 • -4.04) | 0.037 | Jonckheere-Terpstra |
N0 < 10 nodes assessed | 29 | 12.1% | -3.81 (-4.66 • -3.43) | -4.30 (-5.28 • -3.74) | 4.68 (-5.17 • -3.90) | |||||
N1 | 53 | 22.1% | -4.09 (-4.48 • -3.64) | -4.89 (-5.68 • -4.21) | -4.77 (-5.34 • -4.38) | |||||
N2 | 27 | 11.3% | -4.30 (-4.60 • -3.69) | -5.08 (-5.74 • -4.03) | -4.96 (-5.21 • -4.31) | |||||
Tumor grade | Good | 20 | 8.3% | -3.95 (-4.43 • -3.46) | 0.57 | -4.61 (-5.30 • -3.88) | 0.28 | -4.59 (-4.81 • -3.97) | 0.61 | Jonckheere-Terpstra |
Moderate | 192 | 80.0% | -4.14 (-4.60 • -3.61) | -4.69 (-5.33 • -4.08) | -4.72 (-5.20 • -4.15) | |||||
Poor | 20 | 8.3% | -4.10 (-4.60 • -3.74) | -4.95 (-5.87 • -4.35) | -4.78 (-5.24 • -4.08) | |||||
Other | 8 | 3.3% | -3.94 (-4.62 • -3.53) | -4.30 (-5.79 • -3.79) | -4.48 (-4.86 • -4.03) | |||||
Location | Right | 121 | 50.4% | -4.24 (-4.71 • -3.70) | 0.015 | -4.89 (-5.58 • -4.15) | 0.004 | -4.84 (-5.28 • -4.28) | 0.008 | Mann-Whitney U |
Left | 119 | 49.6% | -4.01 (-4.47 • -3.53) | -4.52 (-5.21 • -3.85) | -4.62 (-4.96 • -4.13) | |||||
MSI statusa | MSI | 49 | 20.4% | -4.59 (-5.02 • -4.25) | <0.001 | -5.34 (-5.77 • -4.86) | <0.001 | -5.05 (-5.49 • -4.54) | <0.001 | Mann-Whitney U |
MSS | 190 | 79.2% | -3.96 (-4.47 • -3.49) | -4.46 (-5.21 • -3.92) | -4.63 (-5.08 • -4.03) |