Table 4.
Characteristics of patients with early recurrence vs late recurrence on initial presentation
| Early recurrence (n=10) | Late recurrence (n=5 ) | p-value | |
|---|---|---|---|
| Mean age years (SD) | 58.7 (3.4) | 57 (2.5) | 0.34 |
| Males (%) | 6 (60.0) | 5 (100.0) | 0.23 |
| Asians (%) | 7 (70.0) | 3 (60.0) | 1.00 |
| Hepatitis B (%) | 6 (60.0) | 2 (40.0) | 0.61 |
| Hepatitis C (%) | 5 (50.0) | 2 (40.0) | 1.00 |
| Diabetes | 4 (40.0) | 2 (40.0) | 1.00 |
| Imaging: Mean largest tumor size in cm (SD) | 3.3 (1.3) | 2.8 (0.9) | .48 |
| Explant: Mean largest tumor size in cm (SD) | 4.7 (2.0) | 2.3 (1.0) | 0.05 |
| Explant: Largest tumor >3cm (%) | 5/8* (62.5) | 1/4* (25.0) | 0.55 |
| Imaging: Mean # tumors (SD) | 1.2 (0.6) | 1.2 (0.5) | 1.00 |
| Explant: Mean # tumors (SD) | 3.3 (4.3) | 2.8 (2.9) | 0.82 |
| Explant: >4 tumors (%) | 3/8* (37.5) | 2 (40.0) | 1.00 |
| Well differentiated tumor (%) | 0/8* (0) | 2 (40.0) | 0.13 |
| Met Milan criteria (%) | 9 (90.0) | 4 (80.0) | 1.00 |
| Mean AFP at diagnosis in ng/mL (SD) | 1014.9 (2950.0) | 496.8 (1056.8) | 0.72 |
| AFP>500 ng/mL | 1/9* | 1 | 1.00 |
| AFP>1000 ng/mL | 1/9* | 1 | 1.00 |
| Mean lab MELD score (SD) | 12 (4.2) | 11 (3.5) | 0.71 |
| Received locoregional therapy (%) | 9 (90.0) | 3 (60.0) | 0.24 |
| Mean waiting time (from diagnosis to LT) in days (SD) | 222.6 (185.2) | 135.0 (102.0) | 0.35 |
| Explanted liver met Milan criteria (%) | 3/8* (37.5) | 4 (80.0) | 0.27 |
| Explanted liver with microvascular invasion | 4/8* (50.0) | 1 (20.0) | 0.56 |
*
Data not available for all patients. Number of cases for which data was available is indicated.