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. 2016 Dec 14;58(3):273–280. doi: 10.1093/jrr/rrw112

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© The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 3. — Urinary excretion of the candidate metabolites. (Left) Relative intensity shown as the ratio of intensity of (A) thymidine, cytosine, N-formylmethionine, thymine or imidazoleacetic acid, norepinephrine sulfate and phenyl glucuronide, (B) either succinic acid semialdehyde, acetoacetic acid or 3-methyl pyruvic acid and (C) histamine and 1-methylhistamine, to that of creatinine. (Right) Dose-dependent changes were observed. The time point selected is indicated with circles in the corresponding left panel. The results are presented as mean ± SD. **P < 0.01, *P < 0.05, compared with sham-irradiated samples. Shaded portion shows mean ± 2 SD of each measurement of all sham-irradiated and unirradiated (0 h time point) mice urine. Due to the limit of the measurements and the number of mice available (n = 5), some dose/time points were missed, or are represented by one single, or the average of two, intensity values.