. 2016 Dec 14;58(3):273–280. doi: 10.1093/jrr/rrw112

Table 1.

Nine metabolites satisfying the statistical comparison between mouse urine before and 8 h after 4 Gy irradiation

m/z	Before irradiation		8 h after 4 Gy irradiation		P value^a	Log fold change^b	Predicted metabolites^c
m/z	Average	SD	Average	SD	P value^a	Log fold change^b	Predicted metabolites^c
265.080	0.0048	0.0032	0.13	0.043	0.0009	1.4	Thymidine
112.051	0.0070	0.0038	0.024	0.0064	0.0005	0.54	Cytosine
200.035	0.015	0.0051	0.045	0.0087	0.0001	0.47	N-Formylmethionine
103.039	0.0088	0.0057	0.022	0.0076	0.007	0.40	either Succinic acid semialdehyde, Acetoacetic acid or 3-methyl pyruvic acid
112.087	0.13	0.030	0.30	0.061	0.0005	0.36	Histamine
126.103	0.11	0.027	0.24	0.022	0.000005	0.34	1-Methylhistamine
127.050	0.014	0.0025	0.029	0.0064	0.001	0.33	Thymine or Imidazoleacetic acid
250.039	0.0049	0.0013	0.0020	0.00082	0.002	−0.39	Norepinephrine sulfate
293.064	0.039	0.019	0.0067	0.0041	0.007	−0.77	Phenyl glucuronide

^aWelch's t-test.

^bLog ratio of the average intensity value of ‘8 h after 4 Gy irradiation’ to that of ‘before irradiation’.

^cPredicted formulae of each molecular mass were determined by METLIN, and were searched against the Human Metabolome Database to match previously identified metabolites in normal human urine.