Vein with concentric neointima formation. A lower power image is on the left (A) and a higher power image of a section of the same vein is shown on the right (B). (A) The neointima contains large amounts of blue staining material (proteoglycans, arrowhead), whereas there is prominent concentric accumulation of collagen (yellow stain, long arrow) in the media immediately adjacent to the IEL. No significant inflammatory infiltrates are identified. (B) Discrete microdomains of admixed collagen (yellow) and proteoglycans (blue), indicated by arrows, were observed within the neointima. Some microdomains appeared to have a component of neoangiogenesis (arrowheads). (Movat pentachrome stain)