Figure 3.

Muse cells spontaneously differentiate into glomerular cells in FSGS-SCID mice (7 weeks). Expression of the podocyte markers podocin and WT1, the mesangial cell marker megsin, and the endothelial cell markers vWF and CD31 in the glomerulus of intact SCID and FSGS-SCID of the vehicle, non-Muse, and Muse groups. Human Muse and non-Muse cells were detected as GFP- or human Golgi complex–positive cells. The single-channel images used to produce these figures are shown in Supplemental Result 7. Scale bars, 20 μm.