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. 2017 Jul 3;28(10):2946–2960. doi: 10.1681/ASN.2016070775

Figure 7.

Figure 7.

Recovery of renal functions in FSGS-BALB/c mice at 5 weeks after Muse cell infusion. (A) Urine protein-to-creatinine ratio (urine protein), (B) creatinine clearance, (C) plasma creatinine, and (D) BUN. (A) Urine protein levels were significantly attenuated in the Muse group compared with in the vehicle group at 5 weeks (P<0.05). (B) The Muse group showed significantly higher creatinine clearance compared with the vehicle (P<0.001) and non-Muse (P<0.01) groups, indicating substantial recovery of renal function in the Muse group at 5 weeks. (C) Plasma creatinine was significantly lower in the Muse (P<0.01) and non-Muse (P<0.05) groups than in the vehicle group at 5 weeks. (D) BUN was stable in the Muse group, whereas it was significantly increased in the vehicle and non-Muse groups at 7 weeks. *P<0.05; **P<0.01; ***P<0.001.