Figure 3.

Pregnancy promotes living donor incompatibility to a greater degree than prior transplantation or blood transfusion. (A) Frequency of living donor incompatibility as a function of cPRA for candidates with a history of a sensitizing event. The dotted line represents a 1:1 correlation between living donor incompatibility and cPRA. Transfusion and transplantation groups include both men and women. Number of crossmatched donors is shown in the table for each group. *P<0.001; **P=0.04; ***P=0.01. (B) Frequency of incompatible donor type among candidates grouped by sensitizing event. Number of crossmatched donors is shown in the table for each group. Candidates sensitized by prior transplant or transfusion include men and women, except when crossmatched with an offspring living donor (men only). XM, crossmatched. *P<0.001; **P=0.02.