Table 1.

Associations of preexisting venous intimal hyperplasia index with AVF stenosis, venous blood flow rate, and mean venous diameter on three postoperative ultrasounds

Postoperative Ultrasound Time Point	Stenosis Prevalence			Venous Blood Flow Rate			Mean Venous Diameter
	ORa	95% CI	P Valueb	Relative Δ, %c,d	95% CI	P Valueb	Δ, mmc,e	95% CI	P Valueb
6 wkf	1.07	1.00 to 1.16	0.07	−2.5	−4.6 to −0.4	0.02	−0.018	−0.07 to 0.03	0.46
2 wk	1.00	0.93 to 1.09	0.91	−1.5	−3.3 to 0.5	0.14	−0.002	−0.04 to 0.04	0.92
1 d	1.04	0.94 to 1.16	0.49	−0.2	−1.9 to 1.5	0.81	−0.001	−0.03 to 0.03	0.94

All analyses involve multiply imputed data.

^aOR of developing stenosis per 10% increase in intimal hyperplasia index adjusted for age, sex, black race, chronic dialysis status at time of AVF creation, and AVF location (upper arm versus forearm) as well as inflow artery diameter, mean vein diameter, and brachial artery blood flow rate on preoperative ultrasound, with clinical center modeled as a random variable.

^bP≤0.05 is nominally considered to be statistically significant.

^cAdjusted for age, sex, black race, chronic dialysis status at time of AVF creation, and AVF location (upper arm versus forearm), with clinical center modeled as a random variable.

^dPercent relative change in AVF blood flow rate per 10% increase in intimal hyperplasia index.

^eChange in mean AVF vein diameter (millimeters) per 10% increase in intimal hyperplasia index.

^fWeek 6 results were identified a priori as the primary ultrasound outcomes among the three time points. Hence, these P values were not corrected for testing at multiple time points.