Fig. 3.

Outcome of NAC treatment for the acceleration of thrombosis at 5 months diabetes. (A) Thrombosis in blood vessels of the mouse brain at 20 wks after injection with vehicle (Veh), or streptozotocin to induce diabetes (STZ 20wk). One STZ 20wk group was treated with N-acetylcysteine in drinking water for 3 wks before observation (STZ 20wk +NAC). (B) Comparison of thrombosis times between STZ groups 6wk and 20wk after induction of diabetes. Times to thrombus onset and cessation are shown in postcapillary venules and arterioles in both panels. * P < 0.05 vs. Veh; # P < 0.05 vs. STZ 20wk; ^ P < 0.05 vs. STZ 6wk.