NVP-BVU972 |
ATP competitive Met inhibitor |
c-Met |
43 |
Tivantinib |
ATP non-competitive Met inhibitor |
c-Met |
41,42
|
BMS777607 |
ATP competitive Met inhibitor |
c-Met, RON, Axl, TYRO3 and MER |
44 |
AMG-208 |
ATP competitive Met inhibitor |
c-Met and RON |
45 |
Cabozantinib |
ATP competitive Met inhibitor |
c-Met, VEGFR, RETKIT, FLT3 and TIE2 |
46 |
Foretinib |
ATP competitive Met inhibitor |
c-Met, VEGFR, AXL, PDGFR, KIT, FLT3 and TIE2 |
47,48
|
PF-04217903 |
ATP competitive Met inhibitor |
c-Met |
49,50
|
Crizotinib |
ATP competitive Met inhibitor |
c-Met and ALK |
51,52
|
PHA-665752 |
ATP competitive Met inhibitor |
c-Met, RON, FLK1 and c-Abl |
53,54
|