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. 2017 Sep 28;7:12372. doi: 10.1038/s41598-017-12045-8

Table 2.

TIC frequency of CD24, CD44 and EpCAM cells from xeno-B110 at fourth generation.

Cell Inoculation number Number of tumours/Number of inoculated mice
CD24 CD44 EpCAM
br dim br dim br dim
xeno-B110 500 3/3 1/3 3/3 2/3 3/3 2/3
100 5/6 2/6 4/6 1/5 4/6 1/6
10 1/6 0/6 2/6 0/6 0/6 0/6
Estimated TIC frequency (CI) 1 in 56 (23–135) 1 in 591 (177–1971) 1 in 67 (27–163) 1 in 474 (149–1511) 1 in 104 (42–261) 1 in 509 (162–1605)
p value <0.01 <0.01 0.03
Enrichment factor (br/dim) 10.55 7.07 4.89