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Effect of RA treatment on different histone acetylation and methylation marks. a–h ChIP analysis of the Rarβ promoter from NIH3T3 cells treated with 1 µM RA during 1 h. ChIP was performed with specific antibodies to H3ac a, H4ac b, H3K27ac c, H3K36me3 d, H3K27me3 e, H3K4me1 f, H3K4me2 g, and H3K4me3 h (n = 3). In all graphs data represent mean ± s.e.m. NS—not significant, *P < 0.05 and **P < 0.01. Student’s unpaired two-tailed t-test
