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. 2017 Aug 5;8(40):66747–66757. doi: 10.18632/oncotarget.19965

Table 1. Tumor-of-origin for establishing 3D tumoroid ALI cultures.

ID Anatomical site Pathology evaluation Remarks
CoCa091516 Rectum Rectal cancer Specimen did not yield growing organoid culture, histopathological evaluation of the provided tissue specimen showed only connective tissue.
CoCa100316 Colon Colon adenocarcinoma Organoids and slices were established for short-term culture
CoCa122316 Colon Colon adenocarcioma Organoids and slices were established for short-term culture
LuCa121516 Lung Squamous cell carcinoma (SCC), grade II Organoids and slices were established for short-term culture. Slow growing organoids.
LuCa122716 Lung, right upper lobe, lobectomy Adenocarcinoma, Invasive moderately differentiated lung adenocarcinoma, WHO mixed subtype, papillary 70%, micropapillary 20%, and acinar 10%. Organoids and slices were established for short-term culture. ALI culture show epithelial growth. Epithelial organoids has been subpassaged.
LuCa010517 Lung, left upper lobe, lobectomy Metastatic Squamous Cell Carcinoma (SCC), grade II Organoids and slices were established for short-term culture. Slow growing organoids.
PaCa022417 Pancreas Adenocarcinoma Low tumor yield, specimen contained mostly connective tissue.
ReCa030917 Rectum Rectal adenocarcinoma Tumor tissue content sufficient to establish organoid and 3D cultures
ChCa031017 Liver Cholangiocarcinoma Three-dimensional ALI cultures established and 3D early passage organoid culture.