Table 6. Univariate Cox regression analysis result for TNM stage in the 7^th& 8^th editions, both for clinical & pathological TNM stages separately.

7thcTNM	N	events	MST(m)	HR	P-value
IA	23,531	14,626	29.6	-	-
IB	15,712	11,625	18.9	IB vs IA: 1.44	<0.001
IIA	12,239	9,527	15.2	IIA vs IB: 1.16	<0.001
IIB	11,225	8,865	13.4	IIB vs IIA: 1.05	<0.001
IIIA	62,045	49,851	13.5	IIIA vs IIB: 1.02	<0.04
IIIB	29,763	24,911	11.6	IIIB vs IIIA: 1.14	<0.001
IV	67,596	59,133	5.8	IV vs IIIB: 1.62	<0.001
8thcTNM	N	events	MST(m)	HR	P-value
IA1	1443	799	35.4	-	-
IA2	10,616	6,279	33.7	IA2 vs IA1:1.1	0.11
IA3	11,472	7,548	26.1	IA3 vs IA2: 1.2	< 0.001
IB	10,952	8,003	20.2	IB vs IA3: 1.2	< 0.001
IIA	5,503	4,200	16.0	IIA vs IB: 1.2	< 0.001
IIB	17,644	13,713	15.5	IIB vs IIA: 1.0	< 0.001
IIIA	46,822	37,083	14.3	IIIA vs IIB: 1.1	< 0.001
IIIB	41,140	34,121	11.7	IIIB vs IIIA: 1.2	< 0.001
IIIC	8,923	7,659	10.6	IIIC vs IIIB: 1.1	< 0.001
IVA	57,776	50,236	6.3	IVA vs IIIC: 1.4	< 0.001
IVB	9,820	8,897	3.6	IVB vs IVA: 1.5	< 0.001
7th pTNM	N	events	MST(m)	HR	P-value
IA	339	141	114.8	-	-
IB	224	130	61.1	IB vs IA: 1.66	< 0.001
IIA	171	118	46.3	IIA vs IB: 1.37	0.01
IIB	#	67	48.0	IIB vs IIA: 0.84	0.25
IIIA	#	137	30.1	IIIA vs IIB: 1.67	< 0.001
IIIB	#	*	42.0	IIIB vs IIIA: 0.66	0.32
IV	797	506	21.8	IV vs IIIB: 1.71	0.19
8th pTNM	N	events	MST(m)	HR	P-value
IA1	34	*	-	-	-
IA2	165	64	116.0	IA2 vs IA1:1.87	0.12
IA3	140	70	85.3	IA3 vs IA2: 1.42	0.04
IB	#	91	69.0	IB vs IA3: 1.18	0.29
IIA	#	44	36.2	IIA vs IB: 1.47	0.04
IIB	#	155	50.3	IIB vs IIA: 0.92	0.62
IIIA	182	143	29.3	IIIA vs IIB: 1.45	<0.001
IIIB	#	25	37.3	IIIB vs IIIA: 1.08	0.71
IIIC	-	-	-	-	-
IVA	768	480	23.0	IVA vs IIIB: 1.12	0.58
IVB	29	26	4.7	IVB vs IVA: 3.18	<0.001

(* indicating suppressed numbers for cell size<11 or # indicating the total number from suppressed cell size in Table 5, according to the requirment of the NCDB)(MST,median survival time).