Figure 1. Effects of AR overexpression or knockdown on cell proliferation, migration, invasion, colony formation, and wound-healing in HepG2 cells.

Dot plots showing AR and AKR1B10 mRNA expression in clinical liver samples as studied by Mas et al. (A) Overexpression of AR enhanced whereas knockdown of AR suppressed cell proliferation (B) (n = 6), colony formation (C) (n = 6), migration and invasion (D) (n = 6), and wound healing (E) (n = 3). Data were expressed as the mean ± SEM. **p < 0.01; ***p < 0.001, compared to pFlag-CMV2 or pLV-ctrl transfected cells.