Table 1. Interrelationship of tumor immune microenvironment features.
| Parameter | PD-L1 expression | PD-1 expression | Foxp3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| PD-L1(−) n (%) | PD-L1(+) n (%) | p# | PD-1(−) n (%) | PD-1(+) n (%) | p# | Foxp3(−) n (%) | Foxp3(+) n (%) | p# | |
| CD4 | 567 | 519 | 555 | ||||||
| Absent | 194(63.8) | 110(36.2) | 0.014 | 224(81.5) | 51(18.5) | <0.001 | 193(66.1) | 99(33.9) | 0.003 |
| Present | 141(53.6) | 122(46.4) | 124(50.8) | 120(49.2) | 141(53.6) | 122(46.4) | |||
| CD8 | 571 | 523 | 559 | ||||||
| Absent | 244(60.4) | 160(39.6) | 0.298 | 278(76.6) | 85(23.4) | <0.001 | 247(63.0) | 145(37.0) | 0.044 |
| Present | 93(55.7) | 74(44.3) | 74(46.2) | 86(53.8) | 90(53.9) | 77(46.1) | |||
| PD-1 | 522 | ||||||||
| Absent | 220(62.5) | 132(37.5) | 0.037 | ||||||
| Present | 90(52.9) | 80(47.1) | |||||||
# Pearson χ2 or Fisher's exact test, two-side