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. 2017 Jun 27;8(40):67329–67343. doi: 10.18632/oncotarget.18622

Figure 7. ANCR inhibited breast cancer metastasis in vivo by down regulation of RUNX2.

Figure 7

(A-B) Representative bioluminescence images of lung metastasis in mice injected with cells as indicated via tail veins, and the metastasis were quantified by measuring the photo flux. (*P<0.5, Student’s t-test). (C-E) After 9 weeks, nude mice were sacrificed and lung metastatic nodules were examined macroscopically or detected by H&E staining. The white arrows denoted the metastatic nodules. Error bars in C represent mean± S.D. (***P<0.001, Student’s t-test). Scale bars: 100μm. (F) Representative images of the immunohistochemical staining of RUNX2 in nude mice lung metastasis sections. Scale bars: 50μm.