Table 3. Genotype frequencies distribution and association with liver risk cancer.
SNP-ID | Genotype | Cases | Controls | Without adjustment | With adjustment | ||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | Pa | OR | 95% CI | Pb | ||||
CC | 138 | 202 | 1.00 | – | 1.00 | – | |||
rs6713088 | GC | 242 | 279 | 1.27 | 0.96–1.67 | 0.091 | 1.27 | 0.95–1.69 | 0.100 |
GG | 93 | 82 | 1.66 | 1.15–2.40 | 0.007 | 1.49 | 1.02–2.18 | 0.038 | |
CC | 139 | 180 | 1.00 | – | 1.00 | – | |||
rs12621038 | TC | 245 | 271 | 1.17 | 0.88–1.55 | 0.271 | 1.28 | 0.96–1.71 | 0.098 |
TT | 87 | 112 | 1.01 | 0.70–1.44 | 0.974 | 1.08 | 0.75–1.56 | 0.685 | |
TT | 251 | 252 | 1.00 | – | 1.00 | – | |||
rs1682111 | AT | 181 | 253 | 0.72 | 0.55–0.93 | 0.012 | 0.69 | 0.53–0.91 | 0.007 |
AA | 39 | 59 | 0.66 | 0.43–1.03 | 0.068 | 0.62 | 0.39–0.98 | 0.039 | |
TT | 232 | 306 | 1.00 | – | 1.00 | – | |||
rs843752 | GT | 201 | 214 | 1.24 | 0.96–1.60 | 0.103 | 1.23 | 0.94–1.61 | 0.127 |
GG | 39 | 43 | 1.20 | 0.75–1.91 | 0.451 | 1.13 | 0.70–1.83 | 0.612 | |
AA | 154 | 206 | 1.00 | – | – | 1.00 | – | – | |
rs10439478 | CA | 233 | 261 | 1.19 | 0.91–1.57 | 0.204 | 1.20 | 0.91–1.60 | 0.201 |
CC | 85 | 96 | 1.18 | 0.83–1.70 | 0.355 | 1.31 | 0.90–1.90 | 0.162 | |
GG | 302 | 390 | 1.00 | – | – | 1.00 | – | – | |
rs17045754 | CG | 156 | 160 | 1.26 | 0.96–1.64 | 0.091 | 1.27 | 0.96–1.67 | 0.095 |
CC | 15 | 14 | 1.38 | 0.66–2.91 | 0.392 | 1.37 | 0.63–2.97 | 0.421 | |
TT | 224 | 242 | 1.00 | – | – | 1.00 | – | – | |
rs843720 | GT | 210 | 258 | 0.88 | 0.68–1.14 | 0.327 | 0.85 | 0.65–1.11 | 0.243 |
GG | 38 | 64 | 0.64 | 0.41–1.00 | 0.048 | 0.64 | 0.41–1.01 | 0.057 | |
TT | 235 | 321 | 1.00 | – | – | 1.00 | – | – | |
rs843645 | GT | 206 | 202 | 1.39 | 1.08–1.80 | 0.011 | 1.40 | 1.07–1.82 | 0.014 |
GG | 30 | 41 | 1.00 | 0.61–1.65 | 0.998 | 0.96 | 0.57–1.60 | 0.868 | |
CC | 310 | 392 | 1.00 | – | – | 1.00 | – | – | |
rs11125529 | AC | 149 | 159 | 1.19 | 0.91–1.55 | 0.216 | 1.20 | 0.91–1.58 | 0.204 |
AA | 13 | 13 | 1.27 | 0.58–2.77 | 0.557 | 1.16 | 0.52–2.60 | 0.718 | |
GG | 297 | 377 | 1.00 | – | 1.00 | – | |||
rs12615793 | AG | 160 | 173 | 1.17 | 0.90–1.53 | 0.233 | 1.18 | 0.90–1.55 | 0.243 |
AA | 15 | 14 | 1.36 | 0.65–2.86 | 0.418 | 1.21 | 0.56–2.60 | 0.630 | |
CC | 126 | 178 | 1.00 | – | 1.00 | – | |||
rs843711 | TC | 218 | 278 | 1.11 | 0.83–1.48 | 0.488 | 1.13 | 0.84–1.52 | 0.426 |
TT | 127 | 107 | 1.68 | 1.19–2.37 | 0.003 | 1.62 | 1.13–2.31 | 0.008 | |
CC | 288 | 376 | 1.00 | – | 1.00 | – | |||
rs11896604 | GC | 164 | 167 | 1.28 | 0.98–1.67 | 0.066 | 1.32 | 1.00–1.73 | 0.050 |
GG | 19 | 21 | 1.18 | 0.62–2.24 | 0.610 | 1.08 | 0.56–2.08 | 0.824 | |
CC | 124 | 177 | 1.00 | – | 1.00 | – | |||
rs843706 | AC | 219 | 277 | 1.13 | 0.84–1.51 | 0.414 | 1.14 | 0.84–1.53 | 0.404 |
AA | 128 | 108 | 1.69 | 1.20–2.39 | 0.003 | 1.62 | 1.13–2.31 | 0.008 |
P-values were calculated using the Wald test.
P < 0.05 indicates statistical significance.