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. 2017 Jul 4;8(40):67878–67890. doi: 10.18632/oncotarget.18948

Figure 4. High expression level of α7 mRNA negatively influences survival of patients with SQC-L but not those with ADC-L.

Figure 4

Box-plots show the median and interquartile range of α7 mRNA levels in tumor biopsies from patients with SQC-L or ADC-L surviving or not at 5-year after surgery. Unlike the rest of the analyzed genes, the only significant difference found was associated with α7 gene expression in SQC-L non-survivors (n = 16) and survivors (n = 24). In contrast, no significant changes in tumor expression were observed between ADC-L non-survivors (n = 12) and survivors (n = 26) for any of the nAChR subunit gene. The data were analyzed using the Mann-Whitney non-parametric test; **p < 0.01 after comparing the indicated values; ns = not significant.