Figure 6. Sorafenib rescues primary AML cells from BV6-induced necroptosis.
Primary AML cells were treated for 36 hours with 10 nM BV6 and 20 μM zVAD.fmk in the presence or absence of indicated concentrations of Sorafenib. Cell death was determined by PI staining and flow cytometry. Mean and SD of triplicates are shown; *P < 0.05; **P < 0.01; ***P < 0.001.
