Table 2. List of 26 peptide substrates identified after gefitinib-induced tyrosine phophorylation inhibition which are significantly differentially affected in kinomes of long- versus short-term TNM stage I lung adenocarcinoma patient survivors.

Position of peptide	Sequence	Tyr site	Uniprot	Common name	P value
ART_004_EAIYAAPFAKKKXC	EAIYAAPFAKKK	NA	NA	Artificial peptide substrate	< 0.01
CDK2_8_20	EKIGEGTYGVVYK	[15, 19]	P24941	Cell division protein kinase 2	< 0.01
CTNB1_79_91	VADIDGQYAMTRA	[86]	P35222	Catenin beta-1 (Beta-catenin).	< 0.01
EPHA1_774_786	LDDFDGTYETQGG	[781]	P21709	Ephrin type-A receptor 1 precursor	< 0.01
EPHA2_765_777	EDDPEATYTTSGG	[772]	P29317	Ephrin type-A receptor 2 precursor	< 0.01
EPHA7_607_619	TYIDPETYEDPNR	[608, 614]	Q15375	Ephrin type-A receptor 7 precursor	< 0.01
EPOR_361_373	SEHAQDTYLVLDK	[368]	P19235	Erythropoietin receptor precursor (EPO-R).	< 0.01
EPOR_419_431	ASAASFEYTILDP	[426]	P19235	Erythropoietin receptor precursor (EPO-R).	< 0.01
FER_707_719	RQEDGGVYSSSGL	[714]	P16591	Proto-oncogene tyrosine-protein kinase FER	< 0.01
FES_706_718	REEADGVYAASGG	[713]	P07332	Proto-oncogene tyrosine-protein kinase Fes/Fps	< 0.01
JAK1_1015_1027	AIETDKEYYTVKD	[1022, 1023]	P23458	Tyrosine-protein kinase JAK1	< 0.01
JAK2_563_577	VRREVGDYGQLHETE	[570]	O60674	Tyrosine-protein kinase JAK2	< 0.01
LCK_387_399	RLIEDNEYTAREG	[394]	P06239	Proto-oncogene tyrosine-protein kinase LCK	< 0.01
P85A_600_612	NENTEDQYSLVED	[607]	P27986	Phosphatidylinositol 3-kinase regulatory subunit alpha	< 0.01
PAXI_24_36	FLSEETPYSYPTG	[31, 33]	P49023	Paxillin.	< 0.01
PDPK1_2_14	ARTTSQLYDAVPI	[9]	O15530	3-phosphoinositide-dependent protein kinase 1	< 0.01
PECA1_706_718	KKDTETVYSEVRK	[713]	P16284	Platelet endothelial cell adhesion molecule precursor (PECAM-1)	< 0.01
PGFRB_1002_10	LDTSSVLYTAVQP	[1009]	P09619	Beta-type platelet-derived growth factor receptor precursor	< 0.01
PGFRB_572_584	VSSDGHEYIYVDP	[579, 581]	P09619	Beta-type platelet-derived growth factor receptor precursor	< 0.01
PGFRB_709_721	RPPSAELYSNALP	[716]	P09619	Beta-type platelet-derived growth factor receptor precursor	< 0.01
PLCG1_764_776	IGTAEPDYGALYE	[771, 775]	P19174	1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-1	< 0.01
PRRX2_202_214	WTASSPYSTVPPY	[208, 214]	Q99811	Paired mesoderm homeobox protein 2 (PRX-2)	< 0.01
RET_1022_1034	TPSDSLIYDDGLS	[1029]	P07949	Proto-oncogene tyrosine-protein kinase receptor ret precursor	< 0.01
RON_1346_1358	SALLGDHYVQLPA	[1353]	Q04912	Macrophage-stimulating protein receptor precursor	< 0.01
TEC_512_524	RYFLDDQYTSSSG	[513, 519]	P42680	Tyrosine-protein kinase Tec	< 0.01
ZAP70_485_497	ALGADDSYYTARS	[492, 493]	P43403	Tyrosine-protein kinase ZAP-70	< 0.01