Table 2. Lower expressed or downregulated lncRNAs in NSCLC tissues or cell lines and their functions and probable mechanism.

LncRNA	Function in NSCLC	probable mechanism	cition
TUSC7	associated with worse overall survival		[44]
CASC2	independent predictor for overall survival of NSCLC		[45]
GAS5	indicated a poor prognosis and regulated cell proliferation		[46]
TUG1	related to the proliferation of NSCLC cells	TUG1 RNA could bind to PRC2 in the promotor region of CELF1 and negatively regulated CELF1 expressions	[47]
AK126698	inhibited the proliferation and migration	inhibited the activation of Wnt/β-catenin pathway	[48]
GAS5-AS1	regulated NSCLC cell migration and invasion	through regulation of EMT	[49]