Table 5.
Utility of MELD and Mean Diffusivity (MD) Values (×10−9 M2/s) as Predictors of 90-Day Mortality in Group A.
| Variable | Cut off | N | Death (N) | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy |
|---|---|---|---|---|---|---|---|---|
| MELD | ≥28 | 21 | 16 | 89% | 76.2% | 76.1% | 88.9% | 82.1% |
| MD FWM | >8 | 27 | 17 | 89% | 52.3% | 62.9% | 91.6% | 71.7% |
| MELD + MD FWM | ≥28/>8 | 18 | 16 | 88.9% | 90.4% | 88.9% | 90.4% | 89.7% |
*Mean (95% confidence interval). MELD, model for end stage liver disease; MD, mean diffusivity; FWM, frontal white matter; PPV, positive predictive value; NPV, negative predictive value; AUROC, area under receiver operating curve.