Table 3. Comparison between biofilm production, gelatinase activity and the presence of esp, cyl and gelE genes among invasive, non-invasive and colonizer Enterococcus faecalis isolates.
Virulence factors | Pathogenic isolates n (%) |
Colonizer isolates n (%) N=20 |
P-value | |||
---|---|---|---|---|---|---|
Invasivea (N = 21) |
Non-invasiveb (N = 79) |
Unknown (N = 3) |
P-value | |||
esp+ | 15 (71) | 64 (81) | 3 (100) | 0.5 | 17 (85) | 0.4 |
gelE+ | 16 (76) | 58 (73) | 3 (100) | 0.5 | 11 (55) | 0.06 |
cyl+ | 5 (24) | 37 (47) | 0 | 0.07 | 8 (40) | 0.5 |
esp+,gelE+ | 10 (48) | 50 (63) | 3 (100) | 0.1 | 11 (55) | 0.39 |
esp+,cyl+ | 5 (24) | 36 (46) | 0 | 0.07 | 7 (35) | 0.4 |
gelE+,cyl+ | 5 (24) | 31 (39) | 0 | 0.2 | 3 (15) | 0.08 |
esp+,gelE+,cyl+ | 5 (24) | 31 (39) | 0 | 0.1 | 3 (15) | 0.054 |
esp-,gelE-,cyl- | 0 | 6 (8) | 0 | 0.3 | 2 (10) | 0.8 |
Gelatinase activity | 8 (38) | 27 (34) | 2 (67) | 0.2 | 0 | 0.2 |
Biofilm formation | 6 (29) | 32 (40.5) | 0 | 0.2 | 18 (90) | <0.001 |
MDR | 5 (24) | 26 (33) | 2 (67) | 0.2 | 5 (25) | 0.009 |
aE. faecalis isolated from trachea, cerebrospinal fluid, synovial fluid and blood
bE.faecalis isolated from urine or wound
MDR, multi drug resistance