Table 4. Risk factors associated with renal insufficiency (<60 mL/min per 1.73 m2) in HIV-infected patients in logistic analysis .
| Factors | Crude OR (95% CI) | P value | Adjusted OR (95% CI)a | P value |
|---|---|---|---|---|
| R2 (%) | 6.9 | |||
| Max-rescaled R2 (%) | 20.4 | |||
| Exposure to indinavir | 4.08 (1.66–10.03) | 0.0022 | 3.07 (1.17–8.05) | 0.023 |
| Age (years) (vs. <55) | ||||
| 55–64 | 2.53 (0.94–6.84) | 0.068 | 2.78 (0.96–8.09) | 0.060 |
| ≥65 | 6.32 (1.87–21.39) | 0.003 | 6.84 (1.71–27.34) | 0.007 |
| Route of transmission (vs. heterosexual) | ||||
| Homosexual | 0.89 (0.34–2.37) | 0.821 | 1.13 (0.40–3.16) | 0.816 |
| Bisexual | 0.72 (0.09–5.94) | 0.757 | 0.53 (0.06–4.88) | 0.576 |
| Unknown | 4.79 (1.54–14.92) | 0.007 | 6.15 (1.77–21.33) | 0.004 |
| BMI (kg/m2) (vs. <Q1 (<20.28)) | ||||
| Q1–Q3 (20.28–23.84) | 1.26 (0.39–4.10) | 0.706 | - | |
| ≥Q3 (≥23.84) | 2.62 (0.80–8.62) | 0.113 | - | |
| DM | 5.26 (2.18–12.73) | 0.0002 | 3.03 (1.17–7.82) | 0.022 |
| HTNb | 1.43 (0.58–3.56) | 0.438 | - |
aStepwise selection variables
bInteraction
HIV, human immunodeficiency virus; OR, odds ratio; CI, confidence interval; BMI, body mass index; DM, diabetes mellitus; HTN, hypertension