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. 2017 Sep 22;20(3):217–227. doi: 10.4048/jbc.2017.20.3.217

Table 4. Summary of prospective studies of sentinel node biopsy after neoadjuvant chemotherapy in cN+ axilla.

ACOSOG Z1071 [73] SENTINA [74] SN FNAC [75]
Design Single arm 4 Arms Single arm
No. of patients 756 Arm C (592) 153
Patient population T0-4, N1-2, M0 N1-2, M0 T0-3, N1-2
SLN identification rate (%) 92.9 80.1 87.6
False negative rate (%) 12.6 14.2 9.6
 2 SLNs 21.1 18.5 4.9 ( ≥ 2 SLNs)
 3 SLNs 9.1 7.3 -
 Dual tracer technique 10.8 8.6 5.2
 Inclusion of ypN0(i+) 8.7 - 8.4

SLN=sentinel lymph node.