Table 2. Association of copy number variations with biomarkers.
| Serial No. | Gene | ER | PR | HER2 |
|---|---|---|---|---|
| 1 | LPCAT1 | NA | Positive-amplification | NA |
| 2 | OXCT1 | Positive-amplification | Positive-amplification | NA |
| 3 | DTL | Positive -amplification | Positive-amplification | NA |
| 4 | MMP9 | Positive-amplification | Positive-amplification | NA |
| 5 | COL4A2 | Positive-deletion | Positive-deletion | NA |
| 6 | DHX58 | Positive-deletion | Positive-deletion | NA |
| 7 | NDC80 | Positive-deletion | NA | NA |
| 8 | ZNF385B | Positive-deletion | Positive-deletion | NA |
| 9 | GSTM3 | Positive-deletion | Positive-deletion | Negative-deletion |
| 10 | ECT2 | Positive-amplification | Positive-amplification | NA |
| 11 | RFC4 | Positive-amplification | Positive-amplification | NA |
| 12 | JHDM1D | Positive-amplification | NA | Negative-amplification |
| 13 | AP2B1 | Positive-deletion | Deletion-negative | NA |
| 14 | SLC2A3 | NA | Negative-amplification | NA |
| 15 | EBF4 | Positive-amplification | Positive-amplification | NA |
| 16 | GMPS | Positive-amplification | NA | NA |
| 17 | MELK | Positive-deletion | NA | NA |
| 18 | CENPA | Positive-deletion | Positive-deletion | NA |
| 19 | SERF1A | Negative-deletion | Positive-amplification | NA |
| 20 | DIAPH3 | NA | Positive-deletion | NA |
| 21 | RUNDC1 | Positive-deletion | Negative-deletion | NA |
| 22 | RASSF7 | Positive-deletion | Positive-deletion | NA |
| 23 | GPR180 | Positive-deletion | Positive-deletion | NA |
| 24 | ORC6L | Positive-deletion | NA | NA |
| 25 | GPR126 | Positive-deletion | Positive-deletion | NA |
| 26 | ALDH4A1 | NA | Positive-deletion | NA |
| 27 | SCUBE2 | Positive-deletion | Positive-deletion | NA |
| 28 | ESM1 | Positive-amplification | Positive-amplification | NA |
| 29 | BBC3 | NA | Positive-amplification | NA |
| 30 | GNAZ | Positive-deletion | Positive-deletion | NA |
| 31 | IGFBP5 | Positive-deletion | NA | NA |
| 32 | PITRM1 | Negative-amplification | Negative-amplification | NA |
| 33 | QSOX2 | Positive-deletion | Positive-deletion | NA |
| 34 | MCM6 | Positive-deletion | Positive-deletion | NA |
| 35 | NUSAP1 | Positive-deletion | Positive-deletion | NA |
| 36 | TGFB3 | Positive-deletion | Positive-deletion | NA |
| 37 | PRC1 | Positive-deletion | Positive-deletion | NA |
| 38 | NMU | Positive-deletion | NA | NA |
| 39 | CDCA7 | Positive-deletion | Positive-deletion | NA |
| 40 | FGF18 | Positive-amplification | Positive-amplification | NA |
| 41 | PECI | Positive-deletion | Positive-deletion | Negative-deletion |
| 42 | C16orf61 | Positive-deletion | Positive-deletion | NA |
| 43 | C20orf46 | Positive-amplification | Positive-amplification | NA |
Genes with no association include EXT1, TSPYL5, CCNE2, MTDH, WISP1, CSC42BPA, LIN9, EGLN1, RECQL5, HRASLS, UCHL5, RTN4RL1, DCK, STK32B, C9orf30, FLT1, MS4A7, RAB6B, PALM2.
ER=estrogen receptor; PR=progesterone receptor; HER2=human epidermal growth factor receptor 2; NA=not applicable.