Table 3. Univariable and multivariable analysis of metastatic size related to nodal stage in T1–2 breast cancer patients with no lymphadenopathy.
| Characteristic | Total no. | N1 No. (%) |
N2 or N3 No. (%) |
Univariable | Multivariable | ||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | ||||
| LN metastasis | < 0.001 | 0.001 | |||||
| Micro | 365 | 361 (98.9) | 4 (1.1) | Reference | Reference | ||
| Macro | 1,072 | 994 (92.7) | 78 (7.3) | 7.079 (2.574–19.470) | 5.300 (1.910–14.720) | ||
| Metastatic size (cm) | |||||||
| > 0.2, ≤ 0.5 | 383 | 375 (97.9) | 8 (2.1) | 1.925 (0.575–6.449) | 0.288 | 1.582 (0.468–5.350) | 0.461 |
| > 0.5, ≤ 1.0 | 480 | 439 (91.5) | 41 (8.5) | 8.428 (2.991–23.750) | < 0.001 | 5.967 (2.090–17.020) | 0.008 |
| > 1.0, ≤ 1.5 | 125 | 105 (84.0) | 20 (16.0) | 17.190 (5.749–51.390) | < 0.001 | 12.680 (4.170–38.520) | < 0.001 |
| > 1.5, ≤ 2.0 | 37 | 32 (86.5) | 5 (13.5) | 14.100 (3.606–55.130) | 0.001 | 7.215 (1.760–29.550) | 0.006 |
| >2 | 8 | 5 (62.5) | 3 (37.5) | 54.150 (9.527–307.800) | < 0.001 | 44.790 (7.010–286.200) | < 0.001 |
N1=nodal stage 1; N2=nodal stage 2; N3=nodal stage3; OR=odds ratio; CI=confidence interval; LN=lymph node; Micro=micrometastasis, meta size ≤0.2 cm; Macro=macrometastasis, meta size >0.2 cm.