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. 2017 Sep 22;20(3):297–303. doi: 10.4048/jbc.2017.20.3.297

Table 5. pCR rate according to the intrinsic biological subtypes from CNB in NAC patients.

Subtype* No. of pCR patients NAC group pCR rate (%)
Luminal A 0 10 0
Luminal B– 6 42 14.3
Luminal B+ 8 24 33.3
HER2 6 22 27.3
TNBC 13 49 26.5
Total 33 147 22.4

pCR=pathologic complete response; CNB=core needle biopsy; NAC=neoadjuvant chemotherapy; HER2=human epidermal growth factor receptor 2; TNBC=triple-negative breast cancer.

*Classified from CNB result. luminal A (ER+ and/or PR+, HER2-, Ki-67 low); luminal B- (ER+ and/or PR+, HER2-, Ki-67 high); luminal B+ (ER+ and/or PR+, any Ki-67, HER2+); HER2 (ER-, PR-, HER2+); and TNBC (ER-, PR-, HER2-); Five patients were equivocal HER2 result and cannot classified subtype.