Table III.

GO annotation of differentially expressed microRNA target genes in acute myeloid leukemia samples (top 15).

GO ID	GO Term	Count	P-value
Biological process
GO:0030195	Negative regulation of blood coagulation	21	1.83×10−24
GO:1900047	Negative regulation of hemostasis	21	1.83×10−24
GO:0050819	Negative regulation of coagulation	21	2.65×10−23
GO:0042730	Fibrinolysis	17	1.90×10−22
GO:0040023	Establishment of nucleus localization	16	2.55×10−22
GO:0051961	Negative regulation of nervous system development	14	2.70×10−22
GO:0051964	Negative regulation of synapse assembly	14	2.70×10−22
GO:0030198	Extracellular matrix organization	35	6.31×10−21
GO:0043062	Extracellular structure organization	35	6.58×10−21
GO:0051241	Negative regulation of multicellular organismal process	40	2.08×10−20
GO:0001525	Angiogenesis	35	2.86×10−20
GO:0060252	Positive regulation of glial cell proliferation	15	3.64×10−20
GO:0030320	Cellular monovalent inorganic anion homeostasis	14	3.68×10−20
GO:0030644	Cellular chloride ion homeostasis	14	3.68×10−20
GO:0055064	Chloride ion homeostasis	14	3.68×10−20
Cellular component
GO:0042383	Sarcolemma	33	1.85×10−29
GO:0043220	Schmidt-Lanterman incisure	18	1.80×10−25
GO:0035749	Myelin sheath adaxonal region	17	5.91×10−25
GO:0043218	Compact myelin	18	2.95×10−23
GO:0005925	Focal adhesion	30	1.69×10−21
GO:0005924	Cell-substrate adherens junction	30	3.04×10−21
GO:0030055	Cell-substrate junction	30	1.30×10−20
GO:0070161	Anchoring junction	32	1.09×10−17
GO:0005912	Adherens junction	31	1.73×10−17
GO:0043209	Myelin sheath	18	2.16×10−15
GO:0019897	Extrinsic to plasma membrane	18	2.01×10−13
GO:0019898	Extrinsic to membrane	18	4.02×10−10
GO:0030054	Cell junction	40	1.61×10−09
GO:0014704	Intercalated disc	14	2.10×10−09
GO:0044291	Cell-cell contact zone	14	3.13×10−09
Molecular function
GO:0004859	Phospholipase inhibitor activity	29	1.14×10−44
GO:0055102	Lipase inhibitor activity	29	3.76×10−43
GO:0005544	Calcium-dependent phospholipid binding	35	5.77×10−41
GO:0030234	Enzyme regulator activity	79	1.58×10−23
GO:0004857	Enzyme inhibitor activity	43	1.15×10−22
GO:0005509	Calcium ion binding	65	2.23×10−20
GO:0005546	Phosphatidylinositol-4,5-bisphosphate binding	18	2.28×10−20
GO:0005543	Phospholipid binding	53	7.37×10−19
GO:1901981	Phosphatidylinositol phosphate binding	19	2.81×10−17
GO:0008289	Lipid binding	56	1.54×10−15
GO:0043548	Phosphatidylinositol 3-kinase binding	14	6.81×10−14
GO:0008092	Cytoskeletal protein binding	51	1.35×10−13
GO:0017137	Rab GTPase binding	17	1.55×10−13
GO:0004713	Protein tyrosine kinase activity	25	1.43×10−12
GO:0035091	Phosphatidylinositol binding	22	2.75×10−11

GO, Gene Ontology.