Table 1.
BAL cytology for mice and cotton rats a.
| RSV (−), AS1411 (−) | RSV (−), AS1411 (+) | RSV (+) AS1411 (−) | RSV (+), AS1411 (+) | Statistical Analysis b | ||
|---|---|---|---|---|---|---|
| Mice | Total cell count (×104/mL) | 4.47 ± 0.95 | 5.57 ± 1.18 | 30.60 ± 11.95 | 14.48 ± 3.97 | S |
| % granulocytes | 1.45 ± 0.66 | 2.69 ± 0.63 | 20.32 ± 7.84 | 23.31 ± 9.26 | S | |
| % lymphocytes | 9.79 ± 2.36 | 9.28 ± 2.63 | 44.99 ± 0.18 | 37.66 ± 9.33 | S | |
| % macrophages | 88.72 ± 0.20 | 88.05 ± 0.19 | 34.90 ± 0.14 | 39.00 ± 10.49 | S | |
| Cotton rats | Total cell count (×105/mL) | 2.96 ± 0.73 | 4.56 ± 2.17 | 2.03 ± 1.18 | 3.63 ± 0.98 | NS |
| % granulocytes | 26.6 ± 12.7 | 25.14 ± 13.11 | 21.37 ± 10.80 | 29.95 ± 13.94 | NS | |
| % lymphocytes | 1.48 ± 1.01 | 0.77 ± 0.56 | 1.12 ± 0.60 | 2.60 ± 2.06 | NS | |
| % macrophages | 71.88 ± 13.22 | 74.09 ± 13.57 | 77.51 ± 10.99 | 67.45 ± 12.26 | NS |
a Results displayed as mean ± SEM; b S: p < 0.002 for RSV (+) vs. RSV (−); p > 0.05 for AS1411 (+) vs. AS1411 (−) and for the RSV·AS1411 interaction; NS: p > 0.05 for RSV (+) vs. RSV (−), AS1411 (+) vs. AS 1411 (−) and for the RSV·AS1411 interaction (2-way ANOVA with Bonferroni procedure).