Table 5.

The disease activity index (DAI) of the animals after being treated with TPGS-curcumin, the TPGS-stabilized curcumin nanoparticle, and mesalamine for 15 days.

Day	Group
	a	b	c	d	e
1	0.50 ± 0.55	4.17 ± 1.72	3.67 ± 2.58	3.67 ± 1.86	5.33 ± 2.16
2	0.33 ± 0.82	4.33 ± 2.73	3.83 ± 2.99	3.50 ± 2.74	6.00 ± 2.10
3	0	4.17 ± 2.23	3.50 ± 2.81	1.33 ± 1.97	4.50 ± 0.84
4	0	4.50 ± 2.95	2.17 ± 2.14	1.33 ± 1.97	1.67 ± 0.82
5	0	5.00 ± 3.22	2.67 ± 1.75	0.83 ± 1.60	2.17 ± 1.83
6	0	5.00 ± 2.97	2.33 ± 2.88	0.50 ± 0.84	2.67 ± 1.21
7	0	5.00 ± 2.19	3.17 ± 3.54	1.83 ± 1.94	1.50 ± 1.52
8	0	5.00 ± 2.00	2.00 ± 2.61	1.17 ± 2.04	1.50 ± 1.22
9	0	4.83 ± 2.04	1.8 ± 1.83	0.17 ± 0.41	1.50 ± 1.76
10	0	4.67 ± 2.07	1.17 ± 1.33	0.67 ± 1.63	1.00 ± 1.10
11	0	3.00 ± 1.10	0.50 ± 0.84	0.17 ± 0.41	0.67 ± 1.03
12	0	3.17 ± 1.33	0.50 ± 0.84	0	0.83 ± 1.60
13	0	2.50 ± 1.22	0.33 ± 0.52	0.17 ± 0.41	0.17 ± 0.41
14	0	2.33 ± 0.82	0.33 ± 0.82	0	0.83 ± 1.60
15	0	2.33 ± 0.82	0.67 ± 1.21	0	1.00 ± 1.67

Group a (negative control: healthy, vehicle, water); group b (positive control: TNBS-induced and given only vehicle); group c (TPGS-curcumin suspension 60 mg/kg BW); group d (TPGS-stabilized curcumin nanosuspension 1.8 mg/kg BW); group e (standard drug-mesalamine 180 mg/kg BW). Each group consisted of six rats.