Table 1.

Properties of DASamP2 and 17BIPHE2.

Peptide	DASamP2 a	17BIPHE2 b
Amino acid sequence	IKWKKLLRAAKRIL-NH2	GXKRIVQRIKDXLRNLV-NH2
Peptide template	Polybia-MPI	GF-17
Changes made	D2K, D8R and Q12R	F17X and F27X; X = biphenylalanine
MIC (P. aeruginosa) c	6.25 μM	6.25 μM
HL50	75 μM	225 μM
Cell selectivity	12	36

^a Taken from ref. [28]; ^b Taken from ref. [27]; ^c MIC is the minimal inhibitory concentration; HL₅₀ is the concentration that causes 50% lysis of human red blood cells; cell selectivity (or therapeutic index) is the ratio between HL₅₀ and MIC.