Table 1.

Univariate and Multivariable Associations with FEV₁

Parameter	Univariate Regression		Multivariable Regression
	Regression Coefficient β (95% CI)	P Value	Regression Coefficient β (95% CI)	P Value
Age, yr	−0.017 (−0.024 to −0.011)	<0.001	−0.017 (−0.022 to −0.012)	<0.001
African American race	−0.100 (−0.230 to 0.030)	0.132	−0.212 (−0.302 to −0.123)	<0.001
Female sex	−0.597 (−0.701 to −0.494)	<0.001	−0.570 (−0.644 to −0.496)	<0.001
BMI, kg/m2	−0.001 (−0.011 to 0.009)	0.888	−0.016 (−0.024 to −0.009)	<0.001
Smoking pack-years	−0.002 (−0.004 to 0.001)	0.201	−0.001 (−0.125 to 0.001)	0.701
Current smoker	0.276 (0.162 to 0.390)	<0.001	−0.033 (−0.125 to 0.058)	0.473
CT scanner type	−0.144 (−0.306 to 0.016)	0.078	0.117 (0.011 to 0.222)	0.029
CT emphysema, %	−0.027 (−0.031 to −0.022)	<0.001	−0.015 (−0.020 to −0.009)	<0.001
CT gas trapping, %	−0.019 (−0.022 to −0.017)	<0.001	−0.012 (−0.016 to −0.009)	<0.001
Segmental airway wall area, %	−0.081 (−0.099 to −0.064)	<0.001	−0.066 (−0.079 to −0.052)	<0.001
CV of Jacobian determinant, whole lung	3.412 (2.658 to 3.626)	<0.001	0.821 (0.364 to 1.278)	<0.001

Definition of abbreviations: BMI = body mass index; CI = confidence interval; CT = computed tomography; CV = coefficient of variation.

Adjusted R² = 0.61.