[Table/Fig-3]:
Included PRO studies related to periodontal therapy.
| Authors/ Study design | Participants | Periodontal disease defenition | Intervention/ Comparison | OHQoL† Instrument |
|---|---|---|---|---|
| Lee JM et al., [31] Korea (Longitudinal) | 33 patients Age = 24 to 61 years | Chronic periodontitis | Modified Widman flap surgery | OHQoL† questionnaire |
| D’Avila GB et al., [42], Brazil (Contolled clinical trial) | 60 patients Age >34 years | Eight sites with a PD‡>5 mm and no deeper than 10 mm | Different NSPT§, modalities 1. SRP¶, 2. SRP¶ + Metronidazole, 3. SRP¶ + Professional, plaque removal, 4. SRP¶ +, Metronidazole + Professiona, plaque removal | OHQoL† questionnaire |
| Gamboa AB et al., [43], UK (Prospective pilot study) | 33 patients Age =20 to 60 years | Minimum of two teeth with PD‡> 4 mm | NSPT§ | Emotional intelligence questionnaire by Cooper and Sawaf |
| Ozcelik O et al., [44], Turkey (Randomised controlled trial) | 182 patients | Minimum of eight teeth with attachment loss > 5 mm At least one deep intrabony defect | 1. NSPT§ 2. ST†† 3. ST†† + EMD‡‡ | OHIP§§ – 14 GOHAI¶¶ |
| Wessel JR et al., [37] Ohio (Prospective Clinical) | 26 patients Age= 21 to 70 years | GR††† | CTG‡‡‡ vs FGG§§§ | VAS¶¶¶ |
| Aslund M et al., [45] UK (Randomised controlled trial) | 59 patients Age = 47 to 56 years | Minimum of four site with > 5 mm pockets with 2 mm attachment loss in different quadrants | NSPT§ Piezo ceramic vs Curettes | OHQoL† – UK VAS¶¶¶ SF-MPQ†††† |
| Jowett AK et al., [32] UK (Longitudinal) | 27 patients Age= 21 to 61 years | PD‡> 4 mm in atleast one sextant | 24 hour root surface debridement | OHIP§§– 14 |
| Saito A et al., [38] Japan (Prospective Clinical) | 58 patients Mean age = 53.6 | Min four sites with PD > 4 mm, Radio graphic evidence of bone loss | SRP and oral hygiene Instructions Evaluation after three weeks | OHRQL†††††† (questionnaire) |
| Shah M and Kumar S [41] India (Prospective Clinical) | 50 dentate adults Mean age = 26 and 29 years respectively in control and study groups | At least one proximal site with PD >4 mm | SRP in test group oral hygiene instructions only in control | OHIP§§ – 14 |
| Saito A et al., [18], Japan (Prospective Pilot study) | 21 patients Mean age = 56 | Moderate to severe periodontitis more than two sites with CAL‡‡‡‡>4 mm, or more than two sites with PD‡>5 mm | Phase 1 – baseline Phase 2 (NSPT§) – OHI, SRP¶ under LA. Phase 3 (ST††) – OFD§§§§ + antibiotic +NSAIDs. | OHQoL†-J (Japanese version) |
| Nagarajan S and Chandra RV [33], India (Longitudinal) | 183 patients 18–55 years | Classified into low, moderate and high-risk groups based on PRA¶¶¶¶ model | 1. NSPT§– SRP¶ 2. ST†† 3. Aggressive NSPT§–SRP¶ + local drug Delivery | OHQoL†–UK (United Kingdom version) |
| Wong RM et al., [34], Hong Kong (Longitudinal) | 65 patients 35–65 years of age | Moderate to advanced chronic periodontitis More than two sites with >5 mm PD‡ in each quadrant. | NSPT§– OHI, supra-/ sub-gingival SRP¶ | OHIP§§-4-S (questionnaire) |
| Brauchle F et al., [39] Germany (Prospective Clinical) | 93 patients Age =27-74 | Control group (PD‡< 4 mm, CPI††††† score 0–2), patients with CPI score of 3 (PD‡ = 4–5 mm) and patients with CPI††††† score of 4 (PD‡> 5 mm) | NSPT§ | OHIP§§-German version |
| Douglas de Oliviera DW et al., [40] Brazil (Prospective Clinical) | 22 patients, 25 defects 20 to 49 years of age | Miller class I or II GR‡‡‡‡‡ on maxillary canine or premolar. Presence of dentine hypersensitivity | CAF§§§§§ + CTG‡‡‡ | OHIP§§ - 14 |
| Jonsson B and Ohrn K [23] Sweden (Randomised Controlled Trial) | 87 patients 20 to 65 years of age | Moderate to advanced periodontitis | NSPT§ | GOHAI¶¶ OHQoL† - UK |
| Irani FC et al., [35] U K (Prospective) | 61 Type 2 diabetics 74 non diabetics | Grouped into healthy, gingivitis and periodontitis based on PD, bleeding and radiographic bone loss | NSPT§ comparison between diabetics and non diabetics | OHIP 49 |
| Santuchi CC et al., [46] Brazil (Randomised Controlled Trial) | 90 patients 35 to 60 years of age | Mild to moderate chronic periodontitis | SRP¶ vs One stage full mouth disinfection | OIDP¶¶¶¶¶ OHQoL† |
| Makino-Oi A et al., [1] Japan (Prospective Clinical) | 76 patients above 20years old | Two or more interproximal sites with clinical attachment ≥ 4 mm, not on the same tooth or two or more interproximal sites with probing pocket depth (PD‡) ≥ 5 mm, not on the same tooth, with radiographic evidence of bone loss | 1. Baseline 2. After initial therapy 3. After ST†† or supportive periodontal therapy | OHRQL†††††† (questionnaire) |
| Stefanini M et al., [36] Mutli national (Longitudinal) | 45 patients (90 gingival recessions) | Miller class I or II GR‡‡‡‡‡ | CAF§§§§§ vs CAF§§§§§+ CMX ‡‡‡‡‡‡ | VAS¶¶¶ |
†
Oral health related quality of life
‡
Probing depth,
§
Non-surgical periodontal therapy,
¶
Scaling and root planing,
††
Surgical therapy,
‡‡
Enamel matrix derivative,
§§
Oral Health Impact Profile,
¶¶
General oral health assessment index,
†††
Gingival recession,
‡‡‡
Connective tissue graft,
§§§
Free gingival graft,
¶¶¶
Visual analog scale,
††††
Short form Mc-Gill pain questionnaire,
‡‡‡‡
Clinical attachment level,
§§§§
Open flap debridement,
¶¶¶¶
Periodontal risk assessment,
†††††
Community periodontal index,
‡‡‡‡‡
Gingival recession,
§§§§§
Coronally advanced flap,
¶¶¶¶¶
Oral impact on daily performance,
††††††
Oral health-related quality of life model for dental hygiene,
‡‡‡‡‡‡
Collagen matrix - Xenogenic