[Table/Fig-6]:

Limitations of MTA and Biodentine.

Drawbacks	Related Studies
MTA Long setting time	Torabinajad M et al., 1995 [5], Chng HK et al., 2005 [61] (MTA showed longest setting time when compared to that amalgam).
Difficult handling	Mooney GC and North S 2008 [62] observed that the manipulation of MTA was messy when the moisture was excessive in the preparation which further results in soupy material and hence difficult to use
Discoloration	Accorinte ML et al., 2008 [63] (iron and manganese were the possible elements responsible for discoloration).
Toxic elements in composition	Asgary S et al., 2006 [64] (MTA contains elements like arsenic which diffused into the tissue fluids and could potentially cause toxicity).
High cost
BIODENTINE Poor radio-opacity	Caron G et al., 2014 [24] (despite the presence of zirconium dioxide, Biodentine has unfavourable radiopacity as compare to MTA).
Lower wash out resistance	Grech L et al., 2013 [14], Elumalai D et al., 2015 [60] demonstrated that Biodentine has a high washout, low fluid uptake and sorption values, low setting time and superior mechanical properties.