Figure 6.
Networks of the most persistent pockets found in the KDin, T315I-KDin, Myr/KDin, and Myr/T315I-KDin trajectories. Each pocket (i.e., network node) is represented as a sphere, with the different colors indicating the pocket’s persistency. The pockets are connected via black lines (i.e., network edges). The width of each edge is proportional to the communication frequency. The networks connect the ATP and the myristate binding sites in all systems except T315I-KDin. We performed our analysis considering only pockets having a persistency of at least 20% and above, along the simulation time.