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. 2017 Sep 7;17(9):2048. doi: 10.3390/s17092048

Table 1.

Electrotaxis in conventional and microfluidic devices. EF, Electric Field.

Advantages Drawbacks References
Conventional Devices Dish-based or coverslip-based

  1. Easy operation

  2. Observable cell migration

  1. Bad EF control

  2. Low throughput

 [47,49,62,63,64]
Transwell-based

  1. Easy operation

  2. High throughput

  1. Bad EF control

  2. Large cell input

  3. End-point observation only

 [29]
Microfluidic Devices PDMS-based

  1. Controllable and precise EFs

  2. Reduced Joule heating

  3. High throughput

  4. Observable cell migration

  5. Low cell/reagent consumption

  1. Complicated fabrication

 [66,67,68,69,70,72,73,74,75,76,77,78]
PMMA-based

  1. Controllable and precise EFs

  2. Simple and inexpensive fabrication

  3. Reduced Joule heating

  4. High throughput

  5. Observable cell migration

  6. Low cell/reagent consumption

  1. Possible toxic by-products

 [27,29,35,79,83,84,88,89,91]