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. Author manuscript; available in PMC: 2017 Sep 29.
Published in final edited form as: Nature. 2017 Feb 13;542(7642):479–483. doi: 10.1038/nature21076

Figure 1. A B-lymphoid transcriptional program to regulate factors of glucose uptake and utilization.

Figure 1

a, Western blots of PAX5-, IKZF1-, DN-PAX5-, and DN-IKZF1-induced changes in patient-derived pre-B ALL cells. b, c, Enrichment or depletion (two-way ANOVA) of pre-B ALL cells carrying GFP-tagged PAX5 (b), IKZF1 (c), DN-PAX5 (b) or DN-IKZF1 (c). Glucose uptake and ATP levels were analyzed by two-tailed t-test. Data, mean ± s.d. (n = 3 independent experiments; b,c). For gel source data, see Supplementary Fig. 1.