Table. Selected epidemiologic and clinical elements from patients with fatal cases of RMSF along the US–Mexico border, 2013–2016*.

Element	Case-patient 1	Case-patient 2	Case-patient 3	Case-patient 4
Patient history
Known exposure in RMSF-epidemic area of Mexico	+		+	+
Evidence of receipt of medical care in Mexico	+			+
Prescribed nontetracycline antimicrobial drug	+	+	+	+
Signs and symptoms at initial presentation
Fever	+	+	+	+
Headache		+		+
Nausea/vomiting/diarrhea		+	+
Rash
Severe end-stage manifestations
Skin necrosis	+	+		+
Rash	+	+	+	+
Respiratory failure	+	+	+	+
Disseminated intravascular coagulation		+

*RMSF, Rocky Mountain spotted fever; +, present; blank cells, absent.