TABLE I.
Outcome | BMA* | IC-MS* | IC-TS* | P Value† |
Cellularity (nucleated cells × 106 per mL of aspirate or per g of tissue) | 21.9 (19.0-25.2)‡ | 256 (202-324) | 18.1 (14.2-23.0)‡ | <0.0001 |
CTP-O prevalence (CTP-O per 106 nucleated cells) | 38.1 (25.7-56.6)‡ | 4.28 (2.9-6.4) | 58.9 (39.3-88.6)‡ | <0.0001 |
CTP-O concentration (CTP-O per mL of aspirate or per g of tissue) | 835 (506-1,375) | 1,180 (712-1,977) | 1,155 (689-1,936) | 0.73 |
No. of cells per colony (a metric of proliferation) | 58.29‡ | 35.5§ | 38.2‡§ | 0.013 |
Cell density (a metric of cell migration) (cells per mm2) | 153 (135-173) | 125 (111-142) | 150 (133-170) | 0.051 |
Area of alkaline phosphatase activity per cell (a metric of differentiation) (μm2/cell) | 28.2 (17.0-46.7) | 39.6 (23.9-65.6) | 67.7 (40.8-112) | 0.064 |
The values are given as the geometric mean, with the 95% confidence interval in parentheses.
ANOVA.
No significant difference between the indicated groups according to Tukey test, with alpha = 0.05.
No significant difference between the indicated groups according to Tukey test, with alpha = 0.05.