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Paclitaxel produces mechanical hypersensitivity without altering body weight. (A) Paclitaxel treatment reduced paw withdrawal thresholds to mechanical stimulation relative to rats treated with cremophor vehicle. **p<0.01 paclitaxel- vs. cremophor-treated rats. Two-way ANOVA, two-tailed t-test. (B) Body weight did not differ between groups or relative to baseline (pre-injection) body weight. Data are expressed as mean ± SEM.
