Table 4. Multivariate logistic regression analysis to predict the development of Graves’ disease (GD).

	Genetic variant	Smoking	FH
	AOR (95% CI)	AOR (95% CI)	AOR (95% CI)
rs6553010
AA	1	1.84 (1.20~2.81)*	5.74 (3.50~9.42)*
AG+GG	0.70 (0.50~0.97)*
rs13140012
AA	1	1.81 (1.19~2.77)*	5.66 (3.45~9.29)*
AT+TT	0.70 (0.49~0.96)*
rs2119882
TT	1	1.79(1.17~2.75)*	5.62(3.43~9.22)*
TC+CC	0.67 (0.48~0.93)*
rs13140012/rs2119882
AATT	1	1.81 (1.18~2.76)*	5.76 (3.51~9.47)*
Non AATT	0.61 (0.43~0.85)*

* p < 0.05; AOR, adjusted odds ratio; CI, confidence interval; FH, family history of thyroid disease.