Fig 1. Chronic administration of SS-31 is associated with reduced atherosclerotic lesion area in ApoE^-/- mice.

ApoE^-/- mice fed the Western diet were treated with either 1 mg/kg SS-31 (M1 group) or 3 mg/kg (M3 group) SS-31, or saline (P group) by subcutaneous injection daily for twelve weeks. Representative images of Oil Red O staining of aorta and aortic root are shown in (A) and (C). Quantification of positive area are shown in (B) for (A) and (D) for (C). Data represent the mean ± SEM. * p < 0.05. n = 5 for each group. The black scale bars represent 100 μm.