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Pneumothorax in a 19-year-old man with metastatic osteosarcoma treated with pazopanib, a multitargeted tyrosine kinase inhibitor. Coronal CT images of the right shoulder with lung window (a) and bone window (b) settings show a large soft-tissue mass (arrowhead) arising from the right humerus. The finding represents primary osteosarcoma metastatic to the lung (not shown). Right pneumothorax (*) is seen and is a known complication of pazopanib therapy.
